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Unexpected memories

 Psychology  Comments Off
Jan 312008
 

I had a dream once where there was some kind of gizmo that I could hook up to my brain (painlessly, no mess) and then use to play back my memories on a TV screen, sort of like playing a videotape in a VCR. When I woke up, I felt mildly disappointed, because in the dream I had been happily anticipating the memories I would like to revisit. Maybe this dream is why this story about deep brain stimulation and memory seems so exciting to me. I knew that DBS, in which implanted electrodes are used to stimulate activity in specific parts of the brain, is used to treat Parkinson’s disease, and is being investigated for use in depression. I didn’t realize that it’s evidently sometimes considered for use in morbidly obese people as a means of suppressing appetite. When DBS was applied to the hypothalamus of a man in Canada in such an attempt, he unexpectedly and vividly recalled a memory from about 30 years earlier, watching the remembered scene as an observer. Increasing stimulation of the electrodes made the details come to life more. After several weeks of constant DBS, the man’s performance on memory tests improved.

Memory improvement is of vital interest to those who study various disorders of memory, in particular Alzheimer’s; a small pilot is underway to see if DBS can help people in the early stages of that disease. It seems like this might also have some potential as a way to probe the way long-term memories are stored. I have to admit, though, that the thing that captures my imagination is the thought that maybe someday we really could learn how to stimulate vivid and detailed memories of past events. (And as long as I’m dreaming, I’ll add that it’d be nice if we could do it without implanting those electrodes too deep.)

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 Posted by at 12:54 am  Tagged with:
Jan 282008
 

There seems to be something inherent in human beings that makes them relatively unhappy in their middle years. Researchers analyzed data from people all around the world and found a common pattern of greater happiness in youth and old age and less happiness in midlife. The pattern appears in data on people in 72 different countries, and is consistent across a surprising range of people: rich, poor, childless, with children, male, female, single, married. There is one noticeable difference in the way people are affected: Men and women in England go through their lowest point emotionally at around the same age, but there’s a ten-year difference between men and women in the US (women bottom out around 40 and men around 50). So maybe some factor or factors unknown can influence the timing, but the middle-age slough of despond seems otherwise invariant.

So far, no one knows what it means or why it happens. I like the quote in this press release from a researcher who says that just knowing that it happens and that it’s just a phase could be comforting. (Physically fit 70-year-olds are on average as happy and mentally healthy as a 20-year-old, so there’s something to look forward to.)

As a 46-year-old, I’m wondering if it has to do with the way the future often seems narrower but deeper after a certain point. You’re old enough to realize you have to let go of some of your dreams because they will never happen. The wave function of possibilities you moved in as a young adult has started to collapse because out of all the possibilities, you’ve made choices that have inevitably excluded other choices. There’s definitely a sense of loss involved in watching your horizons narrow, but once you get over that, you have more energy to channel into the things you’ve chosen and with any luck, some of them will bloom for you. And maybe the process of getting over it is a necessary part of learning how to be happier with life and with yourself.

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Jan 262008
 

One of the books I’m reading at the moment is Ilium, a science fiction novel by Dan Simmons that is set in the future and features such exotica as quantum transport, sentient machines, and sophisticated nanotechnology. It’s one of those novels where it takes awhile to see how the various story lines are connected and what the big picture is, so reading it is an exercise in puzzle-solving, with lots of those pleasurable little electric jolts to the brain when you see a connection or fit another piece of the puzzle into place.

The most fascinating thing about the novel to me, though, is the way that literature is woven into the tale. For some reason not yet clear to me, some kind of superhuman or post-human entities are re-enacting the Trojan War on a terraformed Mars, and of course the Iliad is one of the oldest human stories preserved in literature. A consortium of sentient machines from the moons of Jupiter are alarmed by the quantum fluctuations they see on Mars, and a small fleet of the machines is dispatched to investigate.

Two of the sentient machines, possibly my favorite characters in the book so far, are students of human literature. One of them is a fan of Shakespeare and the other has learned quite a lot about the bard but has decided that Proust is really his favorite author. Watching the story unfold itself is fun, but even more fun are the literary quotes these two share in their discussions. The beings running the Trojan War are by and large a repellant lot, and the people left on the surface of the earth are leading a bland existence unseasoned by challenge or meaning (although for a few of them I suspect that is about to change). The idea of a future in which the richness of human literature is cherished most fully by biomechanical creatures is somehow haunting.

So I was in a good frame of mind to investigate this article from The Reader magazine. (For starters, I really like the visual pun in the header.) Philip Davis, a professor of English, describes some work he has begun with a couple of brain imaging specialists to investigate what happens to brains that are exposed to a particular literary device used to great effect by Shakespeare. The device is the shifting in function of a word–for example, using a noun as a verb or a verb as an adjective. He gives several examples, including this from King Lear: “He childed as I fathered.”

Davis was curious about what happens when the brain has to process these shifts in function, which is an especially interesting question in light of some work that suggests that nouns and verbs are processed in different areas of the brain. You would expect a bit of a hesitation as the brain has to decide how to interpret the shifted word. He and a colleague a set of sentences that illustrate function shift, along with some control sentences that are either normal or that use function shift in a meaningless way (e.g., “The pizza was too hot to sing”). EEGs were taken of subjects as they read the sentences (in the future, further tests including fMRI will be done).

The results showed that processing a Shakespearean function shift produced a distinctive pattern of electrical activity–which in itself is pretty cool, to find a link between a particular pattern of word usage and brain activity. The pattern of activity seems to indicate that comprehension was attained but with some additional effort compared to a more normal sentence. Shakespeare, of course, knew nothing of the electrical activity of the brain, but Davis points out how successfully he exploited that extra effort to add emphasis and depth, and to stretch our minds. It’s a small study so far, but it illustrates the potential for productive interaction between science and the humanities.

By the way, this is my thousandth blog post. The event seems to call for a celebration of some sort, so perhaps a bit of chocolate is in order.

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Happy enough

 Psychology  Comments Off
Jan 242008
 

Can you be happy enough? It may sound like an impossibility, like having enough chocolate. However, an analysis of two different data sets suggests that being at the top of the charts for happiness is not necessarily the best place to be. While various measures of well-being (for example, health, success in relationships, earning power) are correlated positively with happiness, those who are pretty happy (8 or 9 on a scale from 1 to 10) earn more money and are more politically engaged and academically successful than the ultra-happy who score a 10 out of 10. This press release on EurekAlert has the details.

I recently read a rather impassioned excerpt from a new book, Against Happiness: In Praise of Melancholy by Eric G. Wilson. The title is daunting, but the kind of happiness Wilson speaks against is connected with a fear of life’s complexities and a bland acceptance of the status quo; he sees this kind of unchallenging happiness as being antithetical to joy and ecstasy as well as to melancholy. One of the points he makes in this excerpt is that an acceptance, rather than avoidance, of the inevitable sadness of life can be an opening into a more complex and nuanced view of the nature of our existence, and it can also be a spur to improve the things that are wrong. The press release about being happy enough make a similar point: Without a certain amount of discontent or unhappiness to alloy our contentment with the world, we are less likely to see much reason to change, even when change is beneficial. This is not to say that the seriously unhappy should not strive to be happier, of course, but if you’re reasonably satisfied with your life, that may be good enough.

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Jan 232008
 

There are two kinds of people in the world…well, actually of course it takes all kinds. But for the purposes of a recent study connecting personality type and self-control, it came down to two different types: promoters and preventers. I gather from this press release on EurekAlert that promoters tend to think in terms of what they would like to gain or accomplish, and preventers in terms of making sure to protect themselves from possible loss or from things going wrong.

When people form strategies for reaching a particular goal, their self-control appears to be stronger if they think in terms of their preferred mode (promotion or prevention)–e.g., if a promoter thinks about how to fulfill a dream, or a preventer thinks about how to avert possible problems. To me one of the most interesting things is that when they were given a choice of strategies, people didn’t necessarily pick the one that fit them better. So of course now I’m wondering which type I am, and how I can use this information. As anyone who knows me well will tell you, I’m a worrywart, which would imply that maybe I’m a preventer, but it seems to me that I work hardest, and am happiest, when I’m trying to achieve something that seems a little bit beyond my grasp.

On a related topic, this year for some reason I mentioned my New Year’s resolutions to several people and found that no one I talked to makes resolutions at the start of the year. That’s not the only time I do it, but for several reasons the start of the new year does mark enough of a shift in my focus that it’s worth thinking about where I want to head next. I started to wonder if anyone made New Year’s resolutions any more, so I was interested in this post from Cognitive Daily. An informal survey of Cognitive Daily readers revealed that some people do still make resolutions on January 1, but that they do better at sticking to commitments they make outside the context of New Year’s resolutions than to the formal lists they draw up at the first of the year. It also turns out that it’s easier to keep your resolutions if you don’t make too many, which makes sense.

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Jan 222008
 

Well-timed sleep seems to provide a host of mental benefits, including a boost in forming new memories and learning new information and skills. One theory for how sleep works these wonders is that it provides our synapses some time to work hard at consolidating memories, without the burden of incoming stimuli. However, a recent study supports another viewpoint, that sleep allows the synapses to quiet down from the day’s work and fall back to a more sustainable level of activity. Using several different methods of measuring the strength of the connections between neurons in rats, researchers found that brain circuits are stronger after a period of wakefulness and weaker after a period of sleep. This suggests that the brain ramps up its activity, and its energy consumption, over the course of the day, to the point that further changes in synapse strength (i.e., learning) are very difficult. Sleeping may provide the synapses with a chance to power down and reset themselves to cope with another day’s incoming stimuli.

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 Posted by at 9:21 pm

Allophilia

 Psychology  Comments Off
Jan 212008
 

Somewhere I saw a mock tirade against gay people that, as best I can remember, went like so: “Gay people want to serve their country in the military. They want to marry their sweethearts; some of them even want to raise children with their sweethearts. They’re just not like us!” The ending implies that a willful ignorance of common ground is involved in some anti-gay sentiments. And certainly the perception of common interests can eat away at traditional barriers based on ethnicity, religion, or any of the other lines that can divide “us” from “them”.

A social psychologist at Harvard, Todd Pittinsky, is investigating the attitudes we tend to have toward “the other”. In particular, he’s exploring whether the current emphasis on tolerance is the best approach to ending prejudiced feelings and behavior, or whether we should in fact be cultivating positive feelings rather than merely seeking to lessen negative ones. This article from the Boston Globe describes his work.

Pittinsky studies allophilia, a love for those different from ourselves (it’s a term he made up based on Greek roots). Using surveys to examine the feelings of those who study or embrace other cultures, he and a colleague identified five components of allophilia: kinship, comfort, affection, engagement, and enthusiasm. With these five components established, researchers can measure allophilia and correlate it with other attributes or behaviors. So far, Pittinsky has found that allophila is a better predictor of helpful behaviors toward a group than a low degree of prejudice toward that group. This suggests that he’s right when he says that decreasing negative feelings (which is pretty much what the tolerance agenda is about) does not necessarily strengthen feelings of affection or appreciation, and that the latter are more important in changing people’s behavior toward another group. Of course, it’s a complicated picture, because sometimes racism or sexism can be linked to positive emotions like protectiveness or admiration (e.g., in the phenomenon of putting women on a pedestal and telling them not to worry their pretty little heads about money).

The article discusses some ramifications of the concept of allophilia, and overall offers some hope that maybe humans can learn to like each other despite, or maybe even because of, their differences.

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Jan 202008
 

Next time you’re looking for something fascinating to browse, check out the Becoming Human web site. The heart of the site is a Flash-based documentary that covers human evolution in five “chapters” narrated by Donald Johanson, one of the discoverers of the early hominid fossil Lucy. Each chapter includes, in addition to the main narrative, a group of exhibits on relevant topics. The documentary also includes a set of hominid profiles, from Ardipithecus ramidus to Homo sapiens, and links to further resources. The site contains lots of information, nicely presented, and offers a lot to the curious browser and also to anyone looking to supplement what a child is learning in school about human origins.

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 Posted by at 6:41 pm